Protein Production

Protein ProductionAmong the several methods currently available for protein purification, only one offers the benefits of a largely matrix-free system, allowing proteins to be purified in their native state. This is important because protein conformation and behavior can be altered due to interactions with membranes or beads, changing the true character of the protein you seek to characterize. Under matrix-free conditions, such as those found within high-performance centrifuges, it becomes possible not only to purify by molecular weight, but also by density and conformation, features unavailable with membrane-based purification techniques. A centrifuge can generate the exact forces needed to purify (and, when needed, quantitate) a protein sample for research or therapeutic use.

Review the basics or polish your technique with our application resources below.

Products for Protein Production

Avanti JXN 26

Avanti JXN-26 Series High Performance

• Features support GMP Compliance
• Quickly isolate cells
• Rapidly remove debris
• Safeguard your final product

Optima AUC Analytical Ultracentrifuge

Optima Analytical Ultracentrifuge

• Characterizes quality
• Consistently verifies purity
• More reliable data analysis
• Real-time data analysis

Optima XPN Ultracentrifuge

• Features support GMP Compliance
• Purify high-quality plasmids for optimal transfection 
tubes in packaging in box

Sterile + Certified Free Tubes

• Maximize consistency of a high-quality final product
• Optimize workflow
• Improve data quality

HarvestLine System Liners

• Reduce biologics exposure
• Minimize sample contamination risks
• Optimize workflows


• Optimize analysis parameters for improved accuracy and correlation to alternative methods
• 24-position auto sampler enables walkway operation


• Quantify or characterize cells with specific biomarkers

*Research Use Only. Not for use in diagnostic procedures.

Biomek 4000

• Precisely track liquid level of tubes
• Provide a distinct interface
• Consistent fraction every time

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Content and Resources

Centrifugation is a complete workflow solution for protein purification and protein aggregation quantification Protein aggregation is a biological phenomenon caused by the abnormal interaction of destabilized proteins. Characterization of protein behavior in solution is critical, as destabilized proteins are susceptible to chemical and physical alterations leading to loss of function.