Analytical Ultracentrifugation

In contrast to other methods used to analyze macromolecules, analytical ultracentrifugation (AUC) enables characterization of samples in their native state under biologically relevant solution conditions. AUC is the most versatile, rigorous and accurate technology available for determining the molecular weight, hydrodynamic and thermodynamic properties of a protein or other macromolecule. It can be used to investigate nearly any type of molecule or particle over a wide range of concentrations and in a diverse variety of solvents. For many research questions, there is no satisfactory analytical substitute for AUC.

Content and Resources

Filter by:
Resource Type
Analytical Ultracentrifuge (AUC) Consumables Guide Learn about options available to you to make the most informed choice and maximize your use of the AUC.
DGE-AUC: Adapting the Power of Density Gradient Separations for Gene Therapy Analytics Learn more about how density gradient ultracentrifugation (DGUC) has been adapted for analytical purposes supporting gene therapy by using an analytical ultracentrifuge (AUC), such as the Optima AUC.