Analytical Ultracentrifugation

In contrast to other methods used to analyze macromolecules, analytical ultracentrifugation (AUC) enables characterization of samples in their native state under biologically relevant solution conditions. AUC is the most versatile, rigorous and accurate technology available for determining the molecular weight, hydrodynamic and thermodynamic properties of a protein or other macromolecule. It can be used to investigate nearly any type of molecule or particle over a wide range of concentrations and in a diverse variety of solvents. For many research questions, there is no satisfactory analytical substitute for AUC.

A new dimension in simplified AUC analysis - Dr. Borries Demeler

Watch this testimonial on the Optima AUC, analytical ultracentrifuge from Dr. Borries Demeler, Professor of Biochemistry and Structural Biology. Dr. Demeler is the creator of Ultrascan, an AUC software analysis program. Hear about his experience with the newest analytical ultracentrifuge.

Experiments

Optical Systems Overview

Immunotherapy Resources

Content and Resources

Filter by:

An Analytical Revolution: Introducing the Next Generation Optima AUC

Principles of Continuous Flow Centrifugation

Looking Under the Hood: Getting Started with the Optima AUC In the webinar we discuss the fundamentals of analytical ultracentrifugation and look at a few sample applications.

Webinar: An Intro to Characterization of Biomolecules Using AUC Analytical Ultracentrifugation (AUC) is one of the most powerful biophysical tools used today for the characterization of biological samples ranging from small drug molecules to intact viruses, vesicles and microparticles

Analytical Ultracentrifugation in Nanoparticle Analysis Joshua Robinson covers the utility of fractionation in the investigation of complex mixtures and polydisperse samples as well as versatility of analytical ultracentrifugation (AUC) for colloid chemistry. He quickly reviews analytical ultracentrifugation (AUC) theory, then discusses deconstructing nano-constructs and how AUC has been used in recent literature to really probe the underlying structure of nano-constructs, nanomaterials. Other topics covered include nanoparticle sample preparation, as well as Beckman Coulter's research and future perspectives.