Immunotherapy involves understanding and harnessing the relationship between the immune system and cancer cells to combat oncogenesis. There are many different potential immunotherapeutic approaches, including cell-based strategies such as adoptive cell transfer, receptor pathway-based strategies such as checkpoint inhibition, and agent-based approaches such as antibody therapy. Genetic engineering can be incorporated into all of these approaches. Gene editing can be used to modulate receptor expression levels, induce the production of certain molecules, change cellular phenotypes, or alter the general intensity of the immune response.

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Efficient Kit-Free Nucleic Acid Isolation uses a Combination of Precipitation and Centrifugation Separation Methods Author: Julia P Luciano-Chadee, Beckman Coulter, Inc., Indianapolis, IN 46268 | Published 2017
Centrifugation is a Complete Workflow Solution for Protein Purification and Protein Aggregation Quantification Author: Julia P Luciano-Chadee | Beckman Coulter Life Sciences, Inc., Indianapolis, IN 46268 | Published 2017
Automating Flow Cytometry Brochure Mitigating sources of variability begins during assay design, continues during analytical method development, and through process monitoring
Cell Therapy: From Research to Commercialization eBook discusses an overview of the steps to commercialization for a cellular therapy, including scaling up production, the advantages of automation, common obstacles, and compliance and regulatory issues
Manufacturing Processes for Engineered T-Cell Therapy – CAR-T Brochure presenting the CAR-T cell therapy workflow and associated product portfolio