Integrated Solutions for Cell Line Development

Stable and transient cell lines expressing recombinant targets such as monoclonal antibodies, ion channels and GPCRs are commonly used in drug screening, gene functional studies, cell line selection and safety assessment studies. The process of developing cell lines starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids, followed by screening and selection based on cell functionality, yield and/or stability. After selection, based on their application, the cell lines and/or the proteins produced by the cells are validated. As the manual screening methods are time-consuming, labor-intensive, and error-prone, there is a great demand for high-throughput, automated screening solutions.

Biomek workstations from Beckman Coulter provide a comprehensive suite of high-throughput automation platforms that are easily integrated to meet each critical step of your cell line development workflow.

  • Stable Cell Line Development
  • Transient Cell Line Development