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The CD2 antigen (LFA-2) is a monomeric 50 kDa glycoprotein. It was formerly described as the sheep red blood cell receptor, causing T-cell rosetting, and has been identified as the ligand for CD58 (LFA-3). It is also a receptor for CD48, CD59 and CD15, which binds to the multimeric form of CD2. CD2 is present on the majority of normal human peripheral blood T lymphocytes and a high percentage of NK cells. It is also expressed by all thymocytes.
Specifications
Target Species
Human
Specificity
CD2
Other Names
CD2, CD58 Ligand, LFA-2, Sheep red blood cell rosettes
Fluorochrome
PC5
Regulatory Status
ASR
Size
1 mL
Format
Liquid
Flow Product Line
IOTest
Clone
39C1.5
Isotype
IgG2a Rat
Clone Description
39C1.5 inhibits sheep erythrocyte rosette formation. It has been used as a CD2 reference monoclonal antibody during HLDA 6 (ref 6T-CD2.7).
Cross Reactivity
Cynomolgus Monkey, Indian Rhesus, Hamadyras Baboon, Capuchin Monkey, Common Marmoset, Olive Baboon, Squirrel Monkey, Equine
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The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.
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