Helios-PB, 22F6, 50 Tests, RUO

Product No:B49311

Helios belongs to the Ikaros transcription factor family. Members of this family are DNA binding proteins containing two-zinc finger N terminal domains and protein binding domain. Helios expression is restricted to the T lymphocytes lineage. Helios is suggested to play an important role in CD4+CD25+FoxP3+ regulatory cells. It has been shown that Helios up-regulates the expression of FoxP3 expression by binding to the FoxP3 promoter. Helios is a highly conserved transcription factor that has 97% sequence homology between human and mice. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.

$441.90 List Price - $441.90


Product Specifications

Target Species Human
Specificity Helios
Fluorochrome Pacific Blue*
Regulatory Status RUO
Size 50 Tests
Format Liquid
Flow Product Line IOTest
Clone 22F6
Isotype IgG Hamster
Clone Description The clone 22F6 reacts with human and mouse Helios.

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