CD64-ECD, 22, 0.5 mL, ASR

Product No:A98434

The CD64 antigen (FcγRI) is a glycoprotein with a molecular weight of 72 kDa. It belongs to the Ig superfamily, consisting of three C2-like Ig domains. It is the high affinity receptor for IgG and is able to bind monomeric human IgG1 and IgG3. This antigen is expressed on macrophages and monocytes. It is also expressed on neutrophils when induced with interferon γ (IFN-γ) and granulocyte colony-stimulating factor (G-CSF).

Product Specifications

Target Species Human
Specificity CD64
Other Names CD64, FcgammaR1, FcgR1, FcγRI, High affinity IgG receptor
Fluorochrome ECD
Regulatory Status ASR
Size 0.5 mL
Format Liquid
Flow Product Line IOTest
Clone 22
Isotype IgG1 Mouse
Clone Description The 22 antibody shows especially high affinity binding to human mononuclear phagocytes. The epitope recognized by this antibody is disctinct from the IgG binding site.
Cross Reactivity Indian Rhesus

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