CD54 Antibodies

The CD54 antigen, previously known as ICAM-1 (InterCellular Adhesion Molecule-1), is a 90 kDa transmembrane glycoprotein. With seven potential N-linked glycosylation sites, its structure, as that of CD50 (ICAM-3) and CD102 (ICAM-2), is related to the Immunoglobulin family. The CD54 antigen mediates the adhesion of T lymphocytes with Antigen-Presenting Cells (APC) and is involved in T cell to T cell and T cell to B cell interactions. It is also involved in the adhesion of monocytes, lymphocytes and neutrophils to activated endothelium. It binds to the integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It is a receptor for the rhinovirus. It is expressed by endothelial cells and by many other cell types upon activation.

Clone: 84H10 Isotype: IgG1 Mouse

84H10 antibody inhibits ICAM-1 mediated adhesion to LFA-1.

Explore CD54 Antibodies

Product Line Specifications

Format Liquid
Specificity CD54
Form PE
Clone 84H10
Isotype IgG1 Mouse
Cross Reactivity Canine
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced IM1239U

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 

Technical Documents