CD54 Antibodies
The CD54 antigen, previously known as ICAM-1 (InterCellular Adhesion Molecule-1), is a 90 kDa transmembrane glycoprotein. With seven potential N-linked glycosylation sites, its structure, as that of CD50 (ICAM-3) and CD102 (ICAM-2), is related to the Immunoglobulin family. The CD54 antigen mediates the adhesion of T lymphocytes with Antigen-Presenting Cells (APC) and is involved in T cell to T cell and T cell to B cell interactions. It is also involved in the adhesion of monocytes, lymphocytes and neutrophils to activated endothelium. It binds to the integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). It is a receptor for the rhinovirus. It is expressed by endothelial cells and by many other cell types upon activation.
Clone: 84H10 | Isotype: IgG1 Mouse |
84H10 antibody inhibits ICAM-1 mediated adhesion to LFA-1. | |
Choose a CD54 Model
Product Line Specifications
Format | Liquid |
Specificity | CD54 |
Form | PE |
Clone | 84H10 |
Isotype | IgG1 Mouse |
Cross Reactivity | Canine |
Target Species | Human |
Flow Product Line | IOTest |
Item Specifications Referenced | IM1239U |
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.