The CD49e antigen is the 160 kDa integrin α5-chain, which is composed of a heavy chain (135 kDa) and a light chain (25 kDa), linked by a disulfide bond. CD49e is non-covalently associated with the 130 kDa integrin β1-chain (CD29 molecule), forming the VLA-5 complex. CD49e is expressed by monocytes, platelets and two myeloid cell lines (U937, K562). It is known as the fibronectin and invasin receptor. It is useful for basic studies of fibronectin-mediated adhesion.
|Clone: SAM1||Isotype: IgG2b Mouse|
|The APO2.7 antibody can be used for the direct quantitation of apoptotic cells by flow cytometry, after permeabilization with digitonin. Use of APO2.7 allows for precise monitoring of the early and late cellular responses during apoptosis.|