CD45RA epitopes are present on all the CD45 restricted molecules in which the exon A is expressed (ABC and AB containing isoforms). Most B lymphocytes express CD45RA isoforms. The differential expression of CD45 isoforms is associated with different functional properties of T lymphocytes. Peripheral T lymphocytes can be divided into two largely distinct populations of CD45RA- CD45RO+ and CD45RA+ CD45RO- cells. CD45RA is expressed by medullar thymocytes and naïve/resting peripheral CD4+ T lymphocytes.
|Clone: 2H4LDH11LDB9 (2H4)||Isotype: IgG1 Mouse|
|Clone: ALB11||Isotype: IgG1 Mouse|
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