CD43-FITC, DFT1, 2 mL, ASR

Product No:IM3264U

The CD43 antigen is a 95-135 kDa heavily O-glycosylated and sialylated single chain membrane glycoprotein. This cell surface mucin-type glycoprotein is also called leukosialin or sialophorin. CD43 antigen is expressed by platelets and by all leucocytes, weakly on resting B lymphocytes but highly after activation. A soluble form of CD43 (galactoglycoprotein) can be detected in plasma. This form is produced by proteolytic shedding of the extracellular portion of the membrane molecule after cell activation.

Product Specifications

Target Species Human
Specificity CD43
Other Names CD43, gp95, gpL115, leukocyte sialoglycoprotein, Leukosialin, sialophorin
Fluorochrome FITC
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone DFT1
Isotype IgG1 Mouse
Clone Description The DFT1 antibody reacts with an extracellular epitope of the CD43 antigen. It is useful for detecting leucocytes by flow cytometry and immunohistochemistry on routinely-fixed and parrafin-embedded tissue sections. The DFT1 antibody is also able to induce homotypic adhesion of leucocytes.
Cross Reactivity Cynomolgus Monkey, Indian Rhesus, Olive Baboon, Ovine

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