CD42a Antibodies
The CD42a antigen (GPIX) is a single-chain transmembrane glycoprotein of 22 kDa that forms a noncovalent complex with CD42b, CD42c and CD42d (GPIbα, GPIbβ, and GPV). The CD42a expression is restricted to platelets and megakaryocytes. The GPIb-IX-V complex is the platelet receptor for von Willebrand factor and is known as von Willebrand's factor-dependent adhesion receptor. Although GPIb-IX-V primarily functions as a platelet receptor for von Willebrand factor (VWF), it can also bind to other ligands present in circulation such as thrombin, P-selectin, integrin αMβ2, factor XI, factor XII, high- molecular-weight kininogen, as well as a number of snake venom proteins.
| Clone: SZ1 | Isotype: IgG2a Mouse |
| The SZ1 monoclonal antibody reacts with the CD42a-d complex but does not recognize GPIb or GPIX individually. | |
Explore CD42a Antibodies
Product Line Specifications
| Format | Liquid |
| Specificity | CD42a |
| Form | FITC |
| Clone | SZ1 |
| Isotype | IgG2a Mouse |
| Target Species | Human |
| Flow Product Line | IOTest |
| Item Specifications Referenced | IM1757U |
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.