CD4-FITC, SFCI12T4D11, 50 Tests, CE, IVD

Product No:6603862

The CD4 antigen is a single-chain transmembrane glycoprotein with a 59 kDa molecular weight. CD4 binds to a non-polymorphic region of MHC Class II molecules and is a co-receptor in MHC Class II restricted antigen-induced activation. CD4 is expressed on the T "helper" lymphocytes. It is present on most thymocytes where it is frequently co-expressed with CD8. CD4 is also expressed on all monocytes, although with a lower density than on T lymphocytes. CD4+ T lymphocytes are active in inducing and helping the synthesis of immunoglobulins by B cells. CD4 is a receptor for the Human Immunodeficiency Virus type I (HIV-1) envelope protein gp120.

Product Specifications

Target Species Human
Specificity CD4
Other Names CD4, T4 antigen
Fluorochrome FITC
Regulatory Status IVD, CE, Japan IVD
Size 50 Tests
Format Liquid
Flow Product Line cyto-stat
Clone SFCI12T4D11
Isotype IgG1 Mouse
Clone Description SFCI12T4D11 monoclonal antibody antagonizes HIV effects in vitro.
Cross Reactivity Hamadyras Baboon, Olive Baboon

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