CD31 Antibodies

The CD31 antigen, also known as Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1), is a transmembrane glycoprotein of 130 kDa related to the immunoglobulin superfamily. It is expressed on stem cells of the myeloid lineage, on platelets and on endothelial cell junctions. CD31 is involved in the migration of leucocytes through the endothelial cell wall, via adhesion to αvβ3 integrin and to CD38. In addition, CD31 participates in outside-in signaling in leucocytes likely through phosphorylation of its intracytoplasmic tyrosine residues 663 and 686 and subsequent association with tyrosine phosphatases SHP-1 and SHP-2. Studies suggest a comparable mechanism of action for CD31 in activation and aggregation of platelets.

Clone: 1F11 Isotype: IgG1 Mouse

Clone: 5.6E Isotype: IgG1 Mouse

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Product Line Specifications

Format Liquid
Specificity CD31
Form Pacific Blue*
Clone 5.6E
Isotype IgG1 Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced B13035

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 

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