CD25-SNv605, B1.49.9, 0.5 mL, ASR

Product No:C78081

The CD25 antigen (IL-2Rα chain, Tac or p55) is a single-chain glycoprotein with a molecular weight of 55 kDa which is the low affinity receptor for IL-2 (IL-2Rα or IL-2R1). In conjunction with CD122 (IL-2Rβ, p75) and CD132 (IL-2Rγ, p64), CD25 antigen forms the high-affinity IL-2R complex. CD25 is highly expressed on regulatory CD4-positive T lymphocytes and undetected on resting CD8 positive lymphocytes. However, all activated T lymphocytes express the CD25 protein. CD25 is also found on a subset of B cells (CD20 positive), on activated monocytes and macrophages, and on T cell clones. It is also expressed on NK cells enriched from peripheral blood lymphocytes by culturing in the presence of IL-2. It is absent from thymocytes, granulocytes, monocytes, resting NK cells, platelets and erythrocytes.

Product Specifications

Format Liquid
Specificity CD25
Form SNv605
Clone B1.49.9
Isotype IgG2a Mouse
Cross Reactivity Cynomolgus Monkey, Hamadyras Baboon, Indian Rhesus, Olive Baboon, Pigtailed Macaque, Sooty Mangabey
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced C78081

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