CD235a (Glycophorin A) Antigen

The CD235a antigen, also called Glycophorin A, is a transmembrane, single-pass glycoprotein that contains carbohydrate, mostly in the form of sialic acid. CD235a has a molecular weight of 10 kDa. It is expressed by erythroid precursors and erythrocytes. Glycophorins A carries the antigen determinants for the MNS blood groups and has been proposed to be an inhibitor of hemagglutination and hemolysis. Glycophorin A binds siglec 5, and may also serves as receptor for cytokines and pathogens, including the malaria parasite, Plasmodium falciparum and some viruses, including influenza virus and hepatitis A virus.


 Clone: 11E4B-7-6 (KC16)  Isotype: IgG1 Mouse

The 11E4B-7-6 (KC16) antibody binds to the amino acid sequence 27-39 of glycophorin A and has no reactivity to glycophorin B. It reacts with immature erythrocytes including erythroblasts, proerythroblasts and reticulocytes.
 

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Product Line Specifications

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