CD21 Antibodies
The CD21 molecule is a 145 kDa type I transmembrane glycoprotein, which belongs to the family of complement regulatory proteins. CD21 is expressed by mature B lymphocytes and is rapidly lost following cellular activation. It is not expressed on early (pre-B) and late (B blast or plasma cell) B ontogeny. On follicular dendritic cells the CD21 antigen is strongly expressed. Expression of CD21 in a subset of T lymphocytes has been reported. Four types of CD21 ligands have been identified: They are products following proteolytic cleavage of the complement protein C3 (i. e. iC3b, C3dg and C3d), the Epstein-Barr (EBV) virus envelope, Interferon α (IFNα) and CD23. CD21 was found to be part of a large complex containing also CD19, and CD81 (also named TAPA-1) suggesting a key-role of CD21 during the immune response.
Clone: BL13 | Isotype: IgG1 Mouse |
Explore CD21 Antibodies
Product Line Specifications
Format | Liquid |
Specificity | CD21 |
Form | Pacific Blue* |
Clone | BL13 |
Isotype | IgG1 Mouse |
Target Species | Human |
Flow Product Line | IOTest |
Item Specifications Referenced | B09982 |
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.