CD20-SNv605, B9E9, 0.5 mL, ASR

Product No:C78079

The CD20 antigen (Bp35) is an integral non-glycosylated membrane protein with four transmembrane domains. Three isoforms (33, 35 and 37 kDa) result from differential phosphorylation within the cytoplasmic domain. CD20 may also exist on the cell surface as a homo-oligomeric complex forming with other molecules a multimeric receptor complex. The expression of CD20 is restricted to B-lineage cells. Its expression occurs early in pre-B lymphocyte development, persists in B-lymphocyte ontogeny and is lost upon ultimate plasma cell differentiation. The CD20 molecule is present on all B lymphocytes whatever the hematopoietic tissue where they are found (peripheral blood, lymph nodes, spleen, tonsil, or bone marrow). The CD20 antigen may be weakly expressed on a subset of resting T lymphocytes. However, CD20 is not expressed on other leucocyte subsets including NK cells, monocytes and granulocytes.

$629.00 List Price - $629.00


Product Specifications

Format Liquid
Specificity CD20
Form SNv605
Clone B9E9
Isotype IgG2a Mouse
Cross Reactivity Cynomolgus Monkey, Hamadyras Baboon, Indian Rhesus, Olive Baboon, Pigtailed Macaque, Sooty Mangabey
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced C78079

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