CD1c-PC5.5, L161, 0.5 mL, ASR

Product No:B46036

The CD1c antigen (also called BDCA-1) is a member of the CD1 family of proteins that are structurally related to MHC class I proteins. CD1c is a membrane glycoprotein with a molecular weight of 43 kDa, non-covalently associated with β2-microglobulin. CD1c antigen is expressed on a major subpopulation of human myeloid dendritic cells. In blood, CD1c is also expressed on a subpopulation of CD19+ small resting B lymphocytes. Its expression has also been detected on cortical thymocytes (weakly), on Langerhans cells and on dendritic cells. CD1c+ myeloid dendritic cells have been designated as type-1 myeloid dendritic cells (MDC1s). It has been reported that CD1c is also expressed on mature T cells in a tightly regulated manner. CD1c is involved in antigen-presentation of glycolipids. It may also act in T cells as an immune regulatory molecule.

Product Specifications

Target Species Human
Specificity CD1c
Other Names CD1c
Fluorochrome PC5.5
Regulatory Status ASR
Size 0.5 mL
Format Liquid
Flow Product Line IOTest
Clone L161
Isotype IgG1 Mouse
Cross Reactivity Ovine

Customers Also Viewed