CD1c Antibodies
The CD1c antigen (also called BDCA-1) is a member of the CD1 family of proteins that are structurally related to MHC class I proteins. CD1c is a membrane glycoprotein with a molecular weight of 43 kDa, non-covalently associated with β2-microglobulin. CD1c antigen is expressed on a major subpopulation of human myeloid dendritic cells. In blood, CD1c is also expressed on a subpopulation of CD19+ small resting B lymphocytes. Its expression has also been detected on cortical thymocytes (weakly), on Langerhans cells and on dendritic cells. CD1c+ myeloid dendritic cells have been designated as type-1 myeloid dendritic cells (MDC1s). It has been reported that CD1c is also expressed on mature T cells in a tightly regulated manner. CD1c is involved in antigen-presentation of glycolipids. It may also act in T cells as an immune regulatory molecule.
Clone: L161 | Isotype: IgG1 Mouse |
Explore CD1c Antibodies
Product Line Specifications
Format | Liquid |
Specificity | CD1c |
Form | PC5.5 |
Clone | L161 |
Isotype | IgG1 Mouse |
Cross Reactivity | Ovine |
Target Species | Human |
Flow Product Line | IOTest |
Item Specifications Referenced | B46036 |
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.