CD183 (CXCR3) Antigen
CD183, also called CXCR3, is a 41 kDa transmembrane G protein-coupled CXC receptor, belonging to the family of chemokine receptors. It has selectivity for IP10, Mig and I-TAC chemokines. Cellular production of CD183 ligands is induced by interferon, suggesting an important role of CD183 in Th1-type inflammatory processes. CD183 signaling induces chemotactic migration in inflammation-associated effector T cells, involving integrin activation and cytoskeletal changes. CD183 is expressed on T cells (Th1), NK cells, dendritic cells, mast cells, eosinophils.
|Clone: G025H7||Isotype: IgG1 Mouse|
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Product Line Specifications
|Form||Alexa Fluor* 488|
|Flow Product Line||IOTest|
|Item Specifications Referenced||B68144|
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.