CD141-FITC, M80, 1 mL, ASR

Product No:B43289

CD141, also known as thrombomodulin (TM) and BDCA-3, is an endothelial cell surface receptor. It is a 75 kD type I membrane glycoprotein and members of C-type lectin family. Two major isoforms exist, differentiated by the presence or not of sulfated glycosaminoglycan at Ser/Thr region. CD141 antigen is expressed on neutrophils, monocytes, platelets, a subpopulation of myeloid dendritic cells, vascular endothelial cells, and keratinocytes. It is a cofactor in the activation of protein C and initiation of the protein C anticoagulant pathway by binding to its ligand thrombin.

$514.60 List Price - $514.60

Product Specifications

Target Species Human
Specificity CD141
Other Names BDCA-3, CD141, Thrombomodulin
Fluorochrome FITC
Regulatory Status ASR
Size 1 mL
Format Liquid
Flow Product Line IOTest
Clone M80
Isotype IgG1 Mouse

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