CD14-RD1, 322A-1, 100 Tests, CE, IVD
The CD14 antigen is a glycosyl-phosphatidylinositol-linked single-chain surface membrane glycoprotein with a molecular weight of 53-55 kDa. It functions as a high affinity receptor for the complex of LipoPolySaccharide (LPS) and the LPS-Binding Protein (LBP). It is found on cells of myelomonocytic lineage. CD14 antigen is strongly expressed on monocytes, macrophages, and weakly on neutrophils. It is also weakly expressed on B lymphocytes, but is absent from T lymphocytes, NK cells, red blood cells and platelets. It is found on Langerhans cells, follicular dendritic cells and histiocytes.
|Other Names||CD14, LPS Receptor|
|Regulatory Status||IVD, CE, Japan IVD|
|Flow Product Line||coulter clone|
|Cross Reactivity||Cynomolgus Monkey, Indian Rhesus, Hamadyras Baboon, Capuchin Monkey, Squirrel Monkey|