The CD13 antigen is a transmembrane glycoprotein with a large extracellular region and a small intracellular NH2-terminal tail. It has a molecular weight of 150 kDa and is expressed on the cell surface as a non-covalently linked homodimer. It is found on most cells of myeloid origin including neutrophils, eosinophils, basophils and monocytes from normal peripheral blood. It is absent from B and T lymphocytes as well as from red blood cells and platelets. This molecule is found on the surface of committed progenitor cells defined as the Granulocyte-Monocyte Colony Forming Units (CFU-GM) in normal bone marrow. There are up to five subpopulations of CD13 molecules possessing different levels of glycosylation, which may explain the different
binding patterns of various CD13 antibodies.
|Clone: 366 (MY7)||Isotype: IgG1 Mouse|
|Clone: SJ1D1||Isotype: IgG1 Mouse|
|Clone: Immu103.44||Isotype: IgG1 Mouse|
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Product Line Specifications
|Cross Reactivity||Olive Baboon|
|Flow Product Line||IOTest|
|Item Specifications Referenced||A46528|
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.