CD11a Antibodies
CD11a (αL integrin, LFA-1 α chain) is a member of the integrin family. Like some other leucocyte integrins (CD11b, CD11c, CD11d), CD11a is non-covalently associated with the β2 integrin subunit CD18. CD11a is a transmembrane glycoprotein of 170 kDa, mainly expressed by leucocytes including monocytes, macrophages, neutrophils, eosinophils, basophils, B and T lymphocytes. Activated platelets also express CD11a and CD18. LFA-1 (CD11a/CD18) promotes homotypic adhesion between lymphoid cells and heterotypic adhesion of leucocytes to the vascular endothelium. LFA-1’s known ligands are Intercellular Adhesion Molecules (ICAM): ICAM-1 (CD54), ICAM-2 (CD102) and ICAM-3 (CD50).
Clone: 25.3 | Isotype: IgG1 Mouse |
Choose a CD11a Model
Product Line Specifications
Format | Liquid |
Specificity | CD11a |
Form | FITC |
Clone | 25.3 |
Isotype | IgG1 Mouse |
Target Species | Human |
Flow Product Line | IOTest |
Item Specifications Referenced | IM0860U |
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.