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The CD106 antigen, VCAM-1 (Vascular Cell Adhesion Molecule-1), is an adhesion molecule which binds to integrin α4/β1 (VLA-4) and integrin α4/β7 on lymphocytes. It is a 110 kDa membrane protein. CD106 antigen is present on activated endothelial cells, tissue macrophages, dendritic cells and bone marrow fibroblasts. It is involved in the adhesion of lymphocytes, monocytes and eosinophils to activated endothelium.
CD106, vascular cell adhesion molecule-1, VCAM-1
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The 1G11 antibody inhibits T lymphocyte adhesion to TNF-stimulated endothelial cells.
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IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
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No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.
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