β2-microglobulin-UNLB, B1G6, 0.2 mg, RUO

Product No:IM0114

The β2-microglobulin is the non-polymorphic non-covalently bound light chain (12 kDa) of the class I major histocompatibility complex (MHC-I) constitutively expressed on the surface of almost all nucleated cell. β2-microglobulin structure, stabilized by a disulfide bound, is similar to an immunoglobulin like domain. β2-microglobulin is required in the endoplasmic reticulum (ER) to associate with the MHC class I heavy molecule to form with other proteins (calreticulin, tapasin, etc.) the loading complex that exits the ER and is transported to the cell surface. After peptide presentation, β2-microglobulin is actively released into circulation.

$313.00 List Price - $313.00


Product Specifications

Target Species Human
Specificity β2-microglobulin
Fluorochrome UNLB
Regulatory Status RUO
Size 0.2 mg
Format Freeze-dried
Clone B1G6
Isotype IgG2a Mouse

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