Solid Phase Reversible Immobilization (SPRI) technology uses paramagnetic beads to selectively bind nucleic acids by type and size.
SPRI beads are directly added to sample reactions.
Nucleic acids are selectively immobilized onto SPRI beads, leaving contaminants in solution.
A magnetic field is used to pull the microparticles out of solution.
Contaminants are aspirated and microparticles are thoroughly washed, yielding high quality nucleic acids.
Purified nucleic acids are easily eluted from the microparticles under aqueous conditions, which provides maximum flexibility for downstream applications.