Streamlining the Steps of the Monoclonal Antibody Workflow

The development of monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs) is a complex process that requires seamless coordination and collaboration among scientific laboratories. Throughout the various stages of discovery and development, data is generated using different instruments across multiple locations.

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Where We Can Help

No matter which stage of the workflow you’re looking at, there’s a good chance you’ll find one of our solutions playing a crucial role.

Our automated liquid handlers and flow cytometers are used in the screening and validation of target genes. You’ll also find those same instruments in cell line development and clone screening, in addition to our Vi-CELL BLU cell viability analyzer and Valita Titer assay used for antibody quantification.

In upstream process development, you’ll again see our cell viability analyzers and Valita Titer assay as well as our Avanti JXN Series high performance centrifuges.

And in downstream process development and manufacturing, both our Avanti JXN Series centrifuges and Optima XPN Series ultracentrifuges are there to help clarify, purify and formulate.

How These Solutions Can Help You

Biomek i-Series Liquid Handlers

Featuring state-of-the-art automation technology, Biomek i-Series liquid handlers offer unparalleled efficiency and versatility for the most demanding workflows. They’re ideal for medium- to high-throughput applications, enable microliter-to-milliliter transfers with precision and speed, and give you the freedom to walk away with confidence.

CytoFLEX Flow Cytometer

CytoFLEX flow cytometers enable you to see what you can’t with other platforms. Praised for its ease-of-use, best-in-class sensitivity and intuitive software, it enables both experienced and novice flow cytometrists to quickly and confidently set up protocols to test a hypothesis, rigorously run a critical assay, and effortlessly export publication-quality data.

CytoFLEX SRT Cell Sorter

With the flexibility to output in a variety of plate and tube formats, an easy-to-clean and easy-to-exchange nozzle, and the ability to sort four populations simultaneously, the CytoFLEX SRT cell sorter gives you powerful, flexible sorting in a compact footprint.

Echo Acoustic Liquid Handlers

Echo acoustic liquid handers use sound energy to precisely transfer liquid without pipette tips, nozzles or tubing. This instrument combines the innovative technologies of Acoustic Droplet Ejection and Dynamic Fluid Analysis to transfer a wide range of fluids accurately and reliably.

Valita Titer Assay for IgG Quantification

The Valita Titer assay is among the fastest, easiest and readily-automatable IgG quantification assays. Available in 96- and 384-well formats, and in two detection range formats—2.5 – 100 mg/L and 100 -2000 mg/L—it enables rapid, high-throughput IgG quantification directly from crude cell culture samples.

Vi-CELL BLU Analyzer

The Vi-CELL BLU analyzer automates the trypan blue dye exclusion method for cell viability and counting using advanced liquid handling and imaging technology. With it in your lab, you’ll benefit from faster sample processing, excellent data reproducibility, greater sample capacity and GMP compliance.

Vi-CELL MetaFLEX Analyzer

The Vi-CELL MetaFLEX analyzer is your solution for fast and reliable analysis of bioanalytes in cell culture media, even with low sample volumes. It evaluates crucial parameters such as pH, glucose, pO2 and pCO2, lactate, potassium, calcium, and sodium, allowing for comprehensive monitoring of metabolic activities.

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For Research Use Only. Not for use in diagnostic procedures.
Valita, Valita Aggregation Pure, Valita Titer and the ValitaCell logo are the trademarks of ValitaCell Ltd in the United States and other countries. ValitaCell is a Beckman Coulter Company.

 

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Let’s talk about how we can help you overcome manual barriers, minimize downtime and reduce time to market.

 

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