ZAP-70 Antibodies
Zap-70, a Syk family protein tyrosine kinase expressed in T and NK cells, plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement. Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues, presumably by two mechanisms: autophosphorylation and transphosphorylation by the Src family tyrosine kinase, Lck. Tyrosine phosphorylation of Zap-70 correlates with its increased kinase activity and downstream signaling events.
| Clone: SBZAP | Isotype: IgG1 Mouse |
| The monoclonal antibody SBZAP was generated against a KLH-peptide sequence corresponding to the human ZAP-70 amino acid residues 280-309. | |
Choose a ZAP-70 Model
Product Line Specifications
| Format | Liquid |
| Specificity | ZAP-70 |
| Form | PE |
| Clone | SBZAP |
| Isotype | IgG1 Mouse |
| Target Species | Human |
| Flow Product Line | IOTest |
| Item Specifications Referenced | B57658 |
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.