Interleukin-2 (IL-2) is a 15-17 kDa cytokine produced and secreted by T cells. The induction of IL -2 secretion is the first step in T cell activation. IL-2 is the major autocrine growth factor for activated T cells and is obligatory for the generation of cytotoxic T cells. IL-2 also promotes the proliferation and the differentiation of NK precursors, B cells and monocytes. Activated CD4+ T cells of the Th1 phenotype produce predominantly IL-2 and Interferon-γ, whereas CD4+ T cells of the Th2 phenotype produce IL-4 and IL-10.
|Clone: IL2.39.1||Isotype: IgG1 Mouse|
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Product Line Specifications
|Flow Product Line||IOTest|
|Item Specifications Referenced||B90436|
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