IFN-γ Antigen
Human Interferon-γ (IFN-γ) is a 20-25 kDa (monomer) pleiotrophic cytokine that is produced by activated T cells and NK cells and is involved in the regulation of almost all immune and inflammatory responses. IFN-γ is involved in the activation, growth and differentiation of T cells, B cells, macrophages, NK cells as well as other cell types. IFN-γ enhances MHC expression on antigen-presenting cells including epithelial, endothelial and connective tissue cell and monocytes cell lines. It also has weak antiviral activity and acts as a macrophage-activating factor (MAF) for tumor cytotoxicity leading to anti-tumor effects.
| Clone: 45.15 | Isotype: IgG1 Mouse |
The FITC- and PE-conjugated forms of the 45.15 antibody are optimized for flow cytometric detection of intracellular IFN-γ in stimulated peripheral blood mononuclear cells (PBMC) after permeabilization with IntraPrep permeabilization reagent. |
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Product Line Specifications
| Format | Liquid |
| Specificity | IFN-γ |
| Form | PE |
| Clone | 45.15 |
| Isotype | IgG1 Mouse |
| Cross Reactivity | Indian Rhesus |
| Target Species | Human |
| Flow Product Line | IOTest |
| Item Specifications Referenced | IM2717U |
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.