Human Interferon-γ (IFN-γ) is a 20-25 kDa (monomer) pleiotrophic cytokine that is produced by activated T cells and NK cells and is involved in the regulation of almost all immune and inflammatory responses. IFN-γ is involved in the activation, growth and differentiation of T cells, B cells, macrophages, NK cells as well as other cell types. IFN-γ enhances MHC expression on antigen-presenting cells including epithelial, endothelial and connective tissue cell and monocytes cell lines. It also has weak antiviral activity and acts as a macrophage-activating factor (MAF) for tumor cytotoxicity leading to anti-tumor effects.
|Clone: 45.15||Isotype: IgG1 Mouse|
The FITC- and PE-conjugated forms of the 45.15 antibody are optimized for flow cytometric detection of intracellular IFN-γ in stimulated peripheral blood mononuclear cells (PBMC) after permeabilization with IntraPrep permeabilization reagent.
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Product Line Specifications
|Cross Reactivity||Indian Rhesus|
|Flow Product Line||IOTest|
|Item Specifications Referenced||IM2717U|
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.