Helios-PB, 22F6, 50 Tests, RUO
Product No:B49311
Helios belongs to the Ikaros transcription factor family. Members of this family are DNA binding proteins containing two-zinc finger N terminal domains and protein binding domain. Helios expression is restricted to the T lymphocytes lineage. Helios is suggested to play an important role in CD4+CD25+FoxP3+ regulatory cells. It has been shown that Helios up-regulates the expression of FoxP3 expression by binding to the FoxP3 promoter. Helios is a highly conserved transcription factor that has 97% sequence homology between human and mice.
*Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.
$491.90 List Price - $491.90
Resources + Tools
Product Specifications
Target Species | Human |
Specificity | Helios |
Fluorochrome | Pacific Blue* |
Regulatory Status | RUO |
Size | 50 Tests |
Format | Liquid |
Flow Product Line | IOTest |
Clone | 22F6 |
Isotype | IgG Hamster |
Clone Description | The clone 22F6 reacts with human and mouse Helios. |