CD95-UNLB, CH11, 0.05 mg, RUO

Product No:IM1504

The CD95 (Fas or APO-1) antigen is a 40-50 kDa transmembrane glycoprotein. It belongs to the Tumor Necrosis Factor (TNF) superfamily and contains three cysteine-rich repeats. This cell surface molecule mediates apoptosis (programmed cell death). CD95 antigen is expressed on a substantial proportion of peripheral blood CD4+ lymphocytes, CD8+ lymphocytes and B lymphocytes but on a minor proportion of NK cells. It is not found on platelets or erythrocytes, but is expressed variably on granulocytes and monocytes. CD95 is strongly up-regulated on activated T cells, B cells, NK cells and thymocytes. Moreover, it is widely expressed on cell lines of T, B, NK and myeloid lineages. Most other tissues express CD95.

$419.90 List Price - $419.90


Product Specifications

Target Species Human
Specificity CD95
Other Names APO-1, CD95, Fas, TNFRSF6
Fluorochrome UNLB
Regulatory Status RUO
Size 0 mg
Format Liquid
Clone CH11
Isotype IgM Mouse
Clone Description The CH11 antibody in vitro induces apoptosis in some CD95 expressing cell lines.

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