CD80-PE, MAB104, 2 mL, ASR

Product No:IM1976U

The CD80 antigen (B7, BB1) is a highly glycosylated single-chain protein. Its extracellular domain consists of two Ig-like domains. This 60 kDa molecule shares with CD86 the capability to be the ligand for two structurally similar molecules expressed on T lymphocytes, CD28 and CD152 (CTLA-4). CD80 antigen is expressed on in vitro activated B lymphocytes after 24h stimulation and at maximal level 48-72h post activation. It is not expressed on the majority of resting B cells from peripheral blood but identifies a subpopulation of B cells that has been previously activated. The antigen is also expressed by HTLV-1 transformed T cells and activated monocytes. CD80 binding provides co-stimulatory signals for T cell activation.

$581.90 List Price - $581.90


Product Specifications

Target Species Human
Specificity CD80
Other Names B7, B7-1, BB1, CD80
Fluorochrome PE
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone MAB104
Isotype IgG1 Mouse
Clone Description The MAB104 monoclonal antibody reacts with in vitro activated B lymphocytes, some B cell lines, and weakly with a small proportion of non-activated B cells. This antibody also reacts with activated T cells but not with peripheral monocytes and T cells.

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