CD62L-PE, DREG56, 2 mL, ASR

IM2214U

$520.00 List Price - $520.00

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Flow Reagents Icon Antibodies and Kits
The CD62L antigen, also called LECAM-1, L-selectin or LAM-1, is a 75 kDa molecule. It acts as the peripheral lymph node homing receptor. It is also involved in lymphocyte binding to High Endothelial Venules (HEV) and in lymphocyte rolling on activated endothelium. CD62L is expressed by B and T lymphocytes, monocytes, neutrophils, eosinophils, and approximately half of the peripheral NK lymphocytes.

Specifications

Target Species Human
Specificity CD62L
Other Names CD62L, LAM-1, LECAM-1, L-selectin
Fluorochrome PE
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone DREG56
Isotype IgG1 Mouse
Clone Description In contrast to other antibodies recognizing this molecule, DREG56 is particularly effective in blocking CD62L mediated lymphocyte binding to lymph node HEV. DREG56 (ref.33) was used as a CD62L reference monoclonal antibody during the HLDA 6.
Cross Reactivity Bovine, Chimpanzee


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The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.