CD61 Antibodies

The CD61 antigen (platelet glycoprotein GPIIIa) is the 110 kDa integrin β3 subunit, concovalently associated with the integrin αIIb chain (CD41, platelet GPIIb) to form the GPIIb-IIIa complex (αIIb-β3 integrin). Independently of CD41, CD61 is also associated with the integrin αV (CD51) to form the vitronectin receptor. CD41/CD61 is expressed only by platelets and megakaryocytes, whereas CD51/CD61 is found on osteoclasts, endothelial cells, macrophages, fibroblasts, smooth muscle, synovial lining cells and renal glomeruli.

Clone: SZ21 Isotype: IgG1 Mouse

The SZ21 antibody is specific for the PlA1, not the PlA2 form of GPIIIa. It inhibits platelet aggregation and secretion induced by collagen, arachidonic acid, and thrombin. This antibody also inhibits fibrinogen binding to human platelets induced by ADP, arachidonic acid and PAF.

Explore CD61 Antibodies

Product Line Specifications

Format Liquid
Specificity CD61
Form PC5.5
Clone SZ21
Isotype IgG1 Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced B21172

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 

Technical Documents