CD32-PE, 20, 2 mL, ASR

IM1935

$490.00 List Price - $490.00

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Flow Reagents Icon Antibodies and Kits
FcγRII proteins exist as six potential isoforms encoded by three genes, designated as A, B, and C. The reported molecular weight of these isoforms are variable between 37 and 43 kDa. All isoforms are similar but not identical in their extracellular regions. The cytoplasmic portion of FcγRIIA and FcγRIIC contains an activatory ITAM motif whereas FcγRIIB contains an inhibitory ITIM motif. Differential splicing of FcγRIIB gene yields to 2 isoforms FcγRIIBb1 and FcγRIIBb2. Monocytes carry all forms of FcγRII, neutrophils carry FcγRIIA and C. FcγRIIB is expressed by B lymphocytes and mast cells.

Specifications

Target Species Human
Specificity CD32
Other Names CD32, Fcgamma receptor type II, FcγRII, gp40
Fluorochrome PE
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone 2E1
Isotype IgG2a Mouse
Clone Description The 2E1 antibody recognizes the antigen isoforms expressed on basophils, neutrophils, eosinophils, platelets and B cells.
Cross Reactivity Cynomolgus Monkey, Indian Rhesus, Olive Baboon, Bovine, Ovine, Mink, Equine


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The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.