CD244-PC5.5, C1.7, 0.5 mL, ASR

Product No:B21171

The CD244 antigen, also called 2B4, is a 38 kDa cell surface signal transduction molecule found on almost all human NK cells. It induces a granule independent killing mechanism by NK effector cells. It is also found on γδ TCR T cells and appoximately half of peripheral αβ TCR CD8+ T cells. It is not found on B or naïve CD8+ T cells. Upon activation, most CD8+ T cells become CD244-positive. However, a small but significant minority of CD8+ T cells remain CD244-negative. This subset is associated with lower cytotoxic activity, lower γ-IFN production and higher IL-4 and IL-10 production. CD244 is a high affinity receptor for CD48.

Product Specifications

Target Species Human
Specificity CD244
Other Names 2B4, C1.7, CD244, p38
Fluorochrome PC5.5
Regulatory Status ASR
Size 0.5 mL
Format Liquid
Flow Product Line IOTest
Clone C1.7
Isotype IgG1 Mouse

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