CD22-PC5.5, SJ10.1H11, 0.5 mL, ASR

The CD22 antigen (BL-CAM) is a transmembrane glycoprotein of the immunoglobulin superfamily. It may be expressed as two different isoforms: the α form (130 kDa) and the β form (140 kDa). CD22 antigen is a B cell restricted antigen expressed in the cytoplasm of B cell progenitors and on the surface of mature B lymphocytes. CD22 expression is lost after B-cell activation, prior to the plasma cell stage. It is absent from peripheral blood T lymphocytes, granulocytes, monocytes.