CD11b-APC-A750, Bear1, 0.5 mL, ASR

A97052

$600.00 List Price - $600.00

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The CD11b antigen is also known as the integrin αM subunit. It combines with the CD18 antigen (integrin β2 subunit) to build the integrin Mac-1 (CD11b/CD18, αMβ2, CR3, iC3bR, Mo-1). CD11b is a type I transmembrane glycoprotein of 170 or 165 kDa under reducing or non-reducing conditions, respectively. CD11b shows 19 potential N-glycosylation sites. Expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen (also known as β2 integrin chain). Together, these two subunits create the CD11b/CD18 integrin, one of the four integrin heterodimers that can be built by the association of CD18 β chain with four distinctive CD11 α chains. CD11b/CD18 is highly expressed on NK Cells, neutrophils, monocytes and macrophages. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.

Specifications

Target Species Human
Specificity CD11b
Other Names alpha-chain of C3bi receptor, alphaM, C3bi receptor, CD11b, gp155/95, integrin a;M-chain, Mac-1
Fluorochrome APC-Alexa Fluor* 750
Regulatory Status ASR
Size 0.5 mL
Format Liquid
Flow Product Line IOTest
Clone Bear1
Isotype IgG1 Mouse
Clone Description Bear1 is a non blocking monoclonal antibody.


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The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.