CD117-PC5, 95C3, 1 mL, ASR

Product No:IM2657U

The CD117 antigen is the 145 kDa protooncogene c-kit. It belongs to the class III receptor tyrosine kinase family. This antigen is the receptor for the stem-cell factor (SCF) encoded by the steel locus (Steel Locus Factor "SLF"). The CD117 antigen is expressed on very few normal bone marrow cells. The majority of CD117+ marrow cells co-express CD34. CD117 is also expressed on mast cells.

Product Specifications

Target Species Human
Specificity CD117
Other Names CD117, c-kit, SCF receptor, SCFR, stem cell factor receptor
Fluorochrome PC5
Regulatory Status ASR
Size 1 mL
Format Liquid
Flow Product Line IOTest
Clone 95C3
Isotype IgG1 Mouse
Clone Description The 95C3 antibody reacts with BFU-E, CFU-GEMM, CFU-GM and CFU-G. The 95C3 antibody reduces the binding of SCF to its receptor to about half of the maximum value.

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