Monoclonal antibody therapies. Their importance in the pharmaceutical market cannot be overstated. As the demand for new therapeutic antibodies continues to grow, more efficient development of stable cell lines becomes increasingly crucial. With the race against time to bring therapies to patients for, among other things, cancer and autoimmune diseases, expediting time to market is vital, and that requires faster, more effective clone screening. The stakes, of course, are high because from one high producing clone can emerge a drug that helps millions, perhaps billions of people.
What if you could automate screening of your most promising clones? What if you could increase throughput while also getting more and earlier answers from your clones?
What if you could increase the certainty of finding the right clones faster?
Now you can find that one ideal clone in much less time because we've combined four technologies from Beckman Coulter Life Sciences to create the Cydem VT automated cell culture system. One powerful tool to help you identify clones with the potential to make a difference in millions of lives and one advanced platform to accelerate clone screening using state of the art automation.
The Cydem VT system is a fully integrated platform for improving and expediting top clone selection. It includes a bioreactor, onboard analytics, automated liquid handling, and validated reagents, all to streamline your process. With the integrated bioreactor module, you can cultivate ninety six five milliliter cultures in deep well microtiter plates, enabling more efficient screening of your clones.
Each of the four twenty four well bioreactor plates features a unique gassing chip for well specific gassing, providing more control over each individual cultivation.
Plus, with online monitoring of pH value and dissolved oxygen level in each of the ninety six cultivation wells, you can maintain optimal pH and dissolved oxygen levels throughout your screening.
From the beginning to the end of your experiment, the integrated cell health module generates regular updates on cell count and viability. This module uses well known Vi-CELL BLU analyzer technology to deliver accurate and precise answers from minimal sample volumes.
The innovative antibody titer module provides you with the valuable insights necessary to make informed decisions about your clone selection.
Because you'll be able to learn more about clone productivity, not just at the end of your screening experiment, but at important points in between.
Running top clone screenings has never been easier with the Cydem VT system automated liquid handler.
By using more controlled fed batch conditions, you'll reduce the risk of selecting suboptimal clones, ensuring that only the best are selected for further study. The automated inoculation and schedule builder functions streamline experiment planning, helping you carry out fed batch pH control and sampling strategies with ease and precision.
Finally, the centralized data capture system ensures that all data from every module is stored in one easy to access location. The user friendly file format simplifies data analysis so you can select your top clones with even greater confidence.
The Cydem VT automated cell culture system is one significant game changer for accelerating cell line development.
It enables automated parallel fed batch cultivation of ninety six clones with pH and dissolved oxygen control, and integrated onboard cell count viability and antibody titer measurement.
Say goodbye to manual clone screening experiments because now you can rely on the power of one.
The Cydem VT automated cell culture system.