RNA Extraction from FFPE Tissue

FormaPure XL RNA

With our SPRI paramagnetic bead-based chemistry, you can extract RNA from even the most challenging formalin-fixed paraffin-embedded (FFPE) tissue samples.

For optimum convenience, you receive knowledgeable support for reagents and automation methods from a single vendor.

  • Fragment analysis shows FormaPure XL RNA kits isolate RNA with the best possible integrity—even from 10+-year-old tissue blocks
  • Performance demonstrated with a variety of sample and tissue types
  • Scalable based on throughput
  • Demonstrated performance with 7x 10 μM curls

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Explore From FFPE Tissue Models

FormaPure XL RNA Visual Workflow

Genomics FormaPure XL RNA Workflow

Product Specifications: FormaPure XL RNA

Application Uses RNA Isolation, RNA Extraction, RNA Sequencing, Nucleic Acid Sample Prep
Format Liquid
Starting Sample Material FFPE (formalin fixed paraffin embedded) tissue.
Automated Available Yes
Item Specifications Referenced C36000

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Total Nucleic Acid Isolation from Formalin-Fixed Paraffin-Embedded (FFPE) Tissues using FormaPure XL Total on a KingFisher™ Duo Prime This protocol demonstrates the FormaPure XL Total performance on the KingFisher Duo Prime purification system. Automating chemistry can reduce the risk of human error, hands-on time (HOT) and total turn-around time (TAT).
Simultaneously DNA and RNA extraction from formalin-fixed paraffin embedded (FFPE) tissue In this poster we present a streamlined NGS ready to use sample prep workflow for FFPE tissue using a product in current development, FormaPure XL Total* (Beckman Coulter Life Science). FormaPure XL Total uses SPRI (Solid Phase Reverse Immobilization) paramagnetic beads to isolate DNA and RNA simultaneously.
Correlation between mutations found in FFPE tumor tissue and paired cfDNA samples In this poster we present a comparison of matched FFPE and plasma samples to determine how many mutations are seen in both tissues. We also look at where the mutational mismatches appear in the chromosome.
AMP 2019: Correlation between mutations found in FFPE tumor tissue and paired cfDNA samples In this poster, presented at AMP 2019, we present a comparison of matched FFPE and plasma samples to determine how many mutations are seen in both tissues. We also look at where the mutational mismatches appear in the chromosome.
A complete workflow for high-throughput isolation of DNA and RNA from FFPE samples using Formapure XL Total on the KingFisher™ Sample Purification System This application note demonstrates the use of FormaPure XL Total, a total nucleic acid extraction kit for FFPE samples, in conjunction with the KingFisher™ Duo Prime Sample Purification System as a potential solution that mitigates some of the challenges with FFPE workflows.

Technical Documents

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