RNA Extraction from FFPE Tissue

FormaPure XL RNA

With our SPRI paramagnetic bead-based chemistry, you can extract RNA from even the most challenging formalin-fixed paraffin-embedded (FFPE) tissue samples.

For optimum convenience, you receive knowledgeable support for reagents and automation methods from a single vendor.

  • Fragment analysis shows FormaPure XL RNA kits isolate RNA with the best possible integrity—even from 10+-year-old tissue blocks
  • Performance demonstrated with a variety of sample and tissue types
  • Scalable based on throughput
  • Demonstrated performance with 7x 10 μM curls

Technical Documents:

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Explore From FFPE Tissue Models

FormaPure XL RNA Visual Workflow

Genomics FormaPure XL RNA Workflow

Product Specifications: FormaPure XL RNA

Application Uses RNA Isolation, RNA Extraction, RNA Sequencing, Nucleic Acid Sample Prep
Format Liquid
Starting Sample Material FFPE (formalin fixed paraffin embedded) tissue.
Automated Available Yes
Item Specifications Referenced C36000

Content and Resources

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Resource Type
Automated Demonstrated Methods for Biomek i-Series Workstations (PDF) Learn more about automated NGS Library Construction and Nucleic Acid Sample Preparation methods for Biomek i-Series workstations
Using FormaPure XL RNA Reagent to Put the Brakes on Prostate Cancer (PDF) Using cancer-specific molecular biomarkers, Dr. Palanisamy’s lab is currently working to understand the genetic complexity of multifocal prostate cancer and its intra- and inter-tumor heterogeneity
Automated TruSeq RNA Sample Preparation from FFPE tissue specimens utilizing the Biomek FXp Liquid Handler This application note describes automated RNA library construction using the Beckman Coulter Biomek FXP Liquid Handler from archival FFPE tissue specimens.
A complete workflow for high-throughput isolation of DNA and RNA from FFPE samples using Formapure XL Total on the KingFisherâ„¢ Sample Purification System This application note demonstrates the use of FormaPure XL Total, a total nucleic acid extraction kit for FFPE samples, in conjunction with the KingFisherâ„¢ Duo Prime Sample Purification System as a potential solution that mitigates some of the challenges with FFPE workflows.
FormaPure XL Data Sheet FormaPure XL reagent kits represent a single chemistry system designed and optimized for use in next-generation sequencing (NGS) as well as other downstream applications including qPCR/ddPCR/PCR

Technical Documents

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