DNA and RNA Extraction from FFPE Tissue

FormaPure XL Total

Extract DNA and RNA from the same formalin-fixed paraffin-embedded tissue sample using SPRI paramagnetic bead-based chemistry.

FormaPure XL reagent kits are available in multiple kit sizes and extraction types based on your application and throughput needs. For optimum convenience, you also receive knowledgeable support for reagents and automation methods from a single vendor.

  • Scalable, single-chemistry system compatible with manual and automated processing (including sample deparaffinization and lysis)
  • Simple workflow with minimal hands-on-time
  • Demonstrated flexibility to accommodate sample input variation
  • High performance for yield, integrity and purity has been shown
  • Performance demonstrated with a variety of sample and tissue types
  • Demonstrated performance with 7x 10 μM curls

Technical Documents:

Explore From FFPE Tissue Models

FormaPure XL Total Visual Workflow

Genomics FormaPure Total XL Workflow

Product Specifications: FormaPure XL Total

Application Uses Nucleic Acid Sample Prep, Total NA Extraction, Total NA Isolation, Total NA Sequencing
Format Liquid
Starting Sample Material FFPE (formalin fixed paraffin embedded) tissue.
Automated Available Yes
Item Specifications Referenced C35991

Content and Resources

Automated Demonstrated Methods for Biomek i-Series Workstations (PDF) Learn more about automated NGS Library Construction and Nucleic Acid Sample Preparation methods for Biomek i-Series workstations
Using FormaPure XL RNA Reagent to Put the Brakes on Prostate Cancer (PDF) Using cancer-specific molecular biomarkers, Dr. Palanisamy’s lab is currently working to understand the genetic complexity of multifocal prostate cancer and its intra- and inter-tumor heterogeneity
A complete workflow for high-throughput isolation of DNA and RNA from FFPE samples using Formapure XL Total on the KingFisherâ„¢ Sample Purification System This application note demonstrates the use of FormaPure XL Total, a total nucleic acid extraction kit for FFPE samples, in conjunction with the KingFisherâ„¢ Duo Prime Sample Purification System as a potential solution that mitigates some of the challenges with FFPE workflows.
Formalin-fixed and non-paraffin-embedded tissue DNA extraction Here we demonstrated a DNA extraction protocol from formalin-fixed and nonparaffin-embedded brain tissue using FormaPure DNA XL kit. In this protocol, protein-DNA cross-links are reversed using heat

Technical Documents

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