CD58 Antigen
CD58 is a glycoprotein of 65-70 kDa, either transmembrane or glycosylphosphatidylinositol (GPI)-anchored. CD58 was first described as the lymphocyte-function associated antigen 3 (LFA-3). LFA-3 was further shown to interact with CD2 suggesting an important role in various immunological responses via T-cell adhesion and activation. CD58 activate the costimulation pathways of T lymphocytes and natural killer (NK) cells, maximizing the cytolysis of target cells by cytotoxic T lymphocytes (CTL) and NK cells. This antigen is widely expressed on leucocytes, erythrocytes and endothelial cells.
| Clone: AICD58 | Isotype: IgG2a Mouse |
| The AICD58 antibody is a blocking antibody in LFA-3 mediated adhesion. This antibody was used as a CD58 reference mAb during HLDA 6. | |
Choose a CD58 Model
Product Line Specifications
| Format | Liquid |
| Specificity | CD58 |
| Form | PC5 |
| Clone | AICD58 |
| Isotype | IgG2a Mouse |
| Target Species | Human |
| Flow Product Line | IOTest |
| Item Specifications Referenced | IM3702 |
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.
