Statistical Inference in the Cytobank Platform

The statistical inference tool in the Cytobank platform enables you to go from raw data to statistical significance in just a few clicks.

It offers several statistical hypothesis testing methods that are widely used by researchers to analyze biological data and empowers you to run a significance test using results from manual gating or machine learning-based analysis, such as FlowSOM, without having to manually export your analysis results outside of the Cytobank platform.

An Introduction to the Tool

In this video, Jason Emo—an application scientist here at Beckman Coulter Life Sciences— shows you:

  • How to leverage the summary plots in the illustration editor, which will enable you to make one-click comparisons of your single cell data
  • How you can use the Cytobank platform to calculate statistical significance for the data in the same summary plots
  • A workflow solution that can enable you to achieve insights for your flow cytometry data even faster than before

 

 

Types of Statistical Inference Tests and Methods

Student’s t-test (also known as t-test)

  • Used to determine if there are any differences in group means between the two groups of samples of an independent variable.

Mann-Whitney U test (also known as the Mann-Whitney-Wilcoxon or Wilcoxon-Mann-Whitney test)

  • Used to determine if the distributions of two sample groups of an independent variable are equal or not.

Paired student’s t-test

  • Used to determine if there are significant differences between groups in an experimental design with paired samples.

Wilcoxon signed-rank test

  • Used to determine if the distributions of two sample groups of an independent variable in a paired experimental design are equal or not.

 

Do you want to learn more about these methods and see examples of how they can be applied?

Learn More

Cytobank Statistical Inference

 

Kruskal-Wallis H test

  • Used to compare more than two groups of an independent variable and determine if all the groups have the distribution or not.

One-way analysis of variance (One-way ANOVA)

  • Used to analyze an independent variable with more than two groups and to determine if there are any differences in group means among the sample groups.

Two-way analysis of variance (Two-way ANOVA)

  • Used to analyze two independent variables simultaneously, where the two independent variables have at least two groups.

 

Cytobank Free Trial

Cytobank is a cloud-based platform for the analysis, storage, and sharing of flow and mass cytometry data. It offers machine learning-assisted analysis of high-dimensional, single-cell data and is designed to let you easily collaborate with colleagues from different departments and regions from any web-enabled device.

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