RNA Extraction from Blood

RNAdvance Blood

Extract high-quality RNA from blood collected in PAXgene and other RNA-preservation tubes.

  • Process built on proprietary SPRI paramagnetic bead-based technology
  • Produces high-integrity RNA for NGS and other PCR-based applications
  • Suitable for manual or automated processing
Resources + Tools
Performance Technical Documents Liquid Handlers Support FAQs

Explore From Blood Models

RNAdvance Blood Workflow Steps

Genomics RNAdvance Blood Workflow

Product Features

Overview
RNAdvance Blood isolates RNA from various RNA preservation tubes (e.g. PAXgene Blood RNA Tubes).

High Quality RNA
The RNAdvance Blood isolation kit purifies intact RNA suitable for downstream PCR-based applications.

Flexible and Scalable
Combining RNAdvance Blood chemistry with our Biomek Workstation offers a high throughput and minimal hand-on solution.

Citations

Beineke, P., Fitch, K., Tao, H., Elashoff, M. R., Rosenberg, S., Kraus, W. E., . . . PREDICT Investigators. (2012, December 3). A whole blood gene expression-based signature for smoking status. BMC Medical Genomics, 5(58). doi:10.1186/1755-8794-5-58

  • Used to extract RNA from PAXgene-collected blood samples

Allaire, N. E., Bushnell, S. E., Bienkowska, J., Brock, G., & Carulli, J. (2013, January 5). Optimization of a high-throughput whole blood expression profiling methodology and its application to assess the pharmacodynamics of interferon (IFN) beta-1a or polyethylene glycol-conjugated IFN beta-1a in healthy clinical trial subjects. BMC Research Notes, 6(8). doi:10.1186/1756-0500-6-8

  • Used to extract RNA from PAXgene-collected blood samples

Disclaimer: Beckman Coulter makes no warranties of any kind whatsoever express or implied, with respect to this protocol, including but not limited to warranties of fitness for a particular purpose or merchantability or that the protocol is non-infringing. All warranties are expressly disclaimed. Your use of the method is solely at your own risk, without recourse to Beckman Coulter. Not intended or validated for use in the diagnosis of disease or other conditions. This protocol is for demonstration only, and is not validated by Beckman Coulter.

Content and Resources

Flyer: Genomic Solutions Collaboration Program (PDF) Through this program, you’ll have exclusive access to Beckman Coulter Life Sciences genomic technologies, data analysis tools and application scientists.
Automated Demonstrated Methods for Biomek i-Series Workstations (PDF) Learn more about automated NGS Library Construction and Nucleic Acid Sample Preparation methods for Biomek i-Series workstations
Total RNA isolation from >50,000 cells A supplemental method utilizing SPRI technology to effectively and efficiently isolate total RNA from large cell numbers.
Evaluate Beckman Coulter's Extraction Kits Review this flyer to determine which reagent kit can best support your workflow based on your extraction needs and starting samples.
FormaPure Total Quick Guide Checklist instructions for using the FormaPure Total extraction and purification kit.

Technical Documents

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