Proteome Profiling of the Tumor Microenvironment: Role of Human Primary Fibroblasts Derived Exosomes in Oral Cancer Progression

Exploring Exosomes and the Tumor Microenvironment

Drs. David Lyden and Dr. Thomas Kislinger cover the topic of exosomes and the tumor microenvironment. 

Exosome Biogenesis and the Budding of Proteins and Viruses

Various models of exosome biogenesis have been proposed. The field however, lacks the robust mechanistic studies needed to obtain a molecular understanding of vesicle secretion. Learn how one lab has taken a cargo-based approach in which the team focuses on the cis-acting signals necessary and sufficient for the budding of specific proteins. Learn from Stephen J Gould why his work supports the hypothesis that the plasma membrane is a major site of exosome budding.

High-Performance Exosome Purification and Characterization via automated Density Gradient

Rapid, accurate exosome purification and sizing with density gradient, ultracentrifugation and dynamic light scattering by Joshua T. Robinson.

Extracellular Vesicles Delivery and RNA Translation

This webinar by Charles Lai, PhD covers visualization and tracking for extracellular delivery and RNA translation using multiplexed reporters.