Lactoferrin-PE, CLB13.17, 2 mL, ASR

Product No:IM2742

Lactoferrin is a 76 kDa single chain polypeptide with iron-binding property. This protein shows structural similarity to the plasma iron-transport protein transferrin. Lactoferrin is involved in various immuno-regulatory functions associated with anti-infective and inflammatory responses such as antibody synthesis, cytokine production, NK cell cytotoxicity, complement activation and lymphocyte proliferation. Lactoferrin synthesis occurs at the myelocytic stage during polymorphonuclear neutrophil (PMN) ontogeny and constitutes a component of secondary (or specific) granules. Unlike the myeloperoxydase, lactoferrin is absent from primary (or azurophilic) granules and appears later during maturation of the granulocytic lineage. Thus, in peripheral blood, intracellular lactoferrin expression is restricted to neutrophils.

Product Specifications

Target Species Human
Specificity Lactoferrin
Fluorochrome PE
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone CLB13.17
Isotype IgG1 Mouse
Clone Description The PE-conjugated CLB-13.17 antibody is optimized for flow cytometric detection of intracellular lactoferrin by flow cytometry after permeabilization with IntraPrep permeabilization reagent.

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